Characterizing proteolytic cleavage site activity using bio-basis function neural networks
نویسندگان
چکیده
منابع مشابه
Characterizing proteolytic cleavage site activity using bio-basis function neural networks
MOTIVATION In protein chemistry, proteomics and biopharmaceutical development, there is a desire to know not only where a protein is cleaved by a protease, but also the susceptibility of its cleavage sites. The current tools for proteolytic cleavage prediction have often relied purely on regular expressions, or involve models that do not represent biological data well. RESULTS A novel methodo...
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در این تحقیق شبکه عصبی مصنوعی برای پیش بینی مقادیر ضریب اطمینان و فاکتور ایمنی بحرانی سدهای خاکی ناهمگن ضمن در نظر گرفتن تاثیر نیروی اینرسی زلزله ارائه شده است. ورودی های مدل شامل ارتفاع سد و زاویه شیب بالا دست، ضریب زلزله، ارتفاع آب، پارامترهای مقاومتی هسته و پوسته و خروجی های آن شامل ضریب اطمینان می شود. مهمترین پارامتر مورد نظر در تحلیل پایداری شیب، بدست آوردن فاکتور ایمنی است. در این تحقیق ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2003
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btg237